SEB Marseille 2008 - Glycosylation
TOPIC: What’s new in experimental glycobiology?
Sponsored by Royal Microscopical Society
Co-organisers
Susan Brooks (Oxford Brookes University)
Ben Appelmelk (Vrije Universiteit Medical Center).
Prof Pauline Rudd (Glycobiology Institute/Dublin-Oxford NIBRT Glycobiology Laboratory)
OUTLINE
We plan a one and a half day session on the topic of ‘What’s new in experimental glycobiology?’ targeted at the non-specialist. We begin with presentations setting the scene and providing necessary background so that the non-specialist can appreciate the importance of glycosylation and the basic principles. From there we will move on to reviewing glycosylation pathways in diverse cell systems (microorganisms, yeasts, plants, parasites, animals etc), introducing advances and challenges in engineering glycosylation pathways in these systems (for example for expression systems and protein engineering) and highlight some of the exciting new frontiers in glycobiology research.
We plan an SEB Symposium series book from the session.
Session Programme - Wednesday 9th July
Chair: Prof. Pauline Rudd (Glycobiology Institute/Dublin-Oxford NIBRT Glycobiology Laboratory)
14:00 Dr Susan Brooks (Oxford Brookes University)
Human N- and O-linked protein glycosylation – an overview [C4.1]
14:30 Prof. Christelle Breton (CERMAV-CNRS)
Structural and functional aspects of glycosyltransferases [C4.2]
15:00 Refreshment Break
15:30 Mr Dieter Schouppe (Ghent University)
Characterization of N-glycosylated receptors for the tobacco lectin in the plant cell nucleus [C4.3]
15:50 Dr Louise Royle (Ludger Ltd)
Introduction to analytical tools for glycan analysis [C4.4]
16:20 Dr Susan Brooks (Oxford Brookes University)
Glycosylation in diverse cell systems – similarities, differences and challenges [C4.5]
Thursday 10th July
Chair: Dr Susan Brooks (Oxford Brookes University)
09:30 Dr B. J. Appelmelk (VUmc Vrije Universiteit Medical Center)
Glycosylation in (Myco-) bacteria [C4.6]
10:00 Dr Cornelis H Hokke (Leiden University Medical Center)
Parasite glycobiology: schistosome glycans in parasite-host interaction and development [C4.7]
10:30 Refreshment Break
11:00 Dr Frans Klis (University of Amsterdam)
Mass spectrometric explorations of the fungal wall proteome [C4.8]
11:30 Dr Muriel Bardor (University of Rouen)
Plant N-glycosylation: an engineered pathway for the production of therapeutical plant-derived glycoproteins [C4.9]
12:00 Lunch
Chair: Dr Ben Appelmelk (VUmc Vrije Universiteit Medical Center)
13:00 Prof. Pauline M Rudd (Glycobiology Institute/Dublin-Oxford NIBRT Glycobiology Laboratory)
Integrated strategy for identifying and screening potential cancer biomarkers [C4.10]
13:30 Miss Hannah Lomax-Browne (Oxford Brookes University)
Interactions between Cancer Cell Glycans and Endothelial Cells during Adhesion and Transmigration Events in Metastasis. [C4.11]
14:00 Prof. Peter Seeberger (Swiss Federal Institute of Technology)
Glycan Arrays [C4.12]
14:30 Refreshment Break
15:00 Dr Teunis Geijtenbeek (VUMC)
C-type lectins on dendritic cells induce Raf-1 signaling to dictate adaptive immune responses against pathogens [C4.13]
15:30 Dr Martin Franck (German Cancer Research Centre, Heidelberg)
Glycosylation - bioinformatics & modelling [C4.14]
16:00 Prof. Peter Seeberger (Swiss Federal Institute of Technology )
Synthetic carbohydrate vaccines [C4.15]
