SEBatMarseille2008
Physiological Strategies to Optimize Oxygen Delivery
Session organised by Dr Colin Brauner (University of British Columbia) and Dr David McKenzie (CNRS Montpellier)
Ensuring and optimising oxygen delivery to respiring tissues has been a major driving force in the evolution of physiological systems and environmental adaptation in animals. Some key examples in the vertebrates include evolution of the Root effect, erythrocytes providing a controlled environment for respiratory pigments; the air-breathing strategies in fishes that led to the subsequent conquest of land, and the development of a divided circulation. The systems and strategies to optimise oxygen delivery have proven to be of enormous diversity and complexity. Despite a growing knowledge base from mechanistic studies, comparative physiologists still have an incomplete understanding of their function. This session will comprise talks at various levels of biological organisation, from molecular to cellular (haemoglobin and red blood cell), to organ systems (control of regional blood flow) and the whole animal (cardiovascular dynamics and metabolic responses). It will last 1.5 days, with a mixture of invited speakers and submitted presentations, both talks and posters. Presentations from early career scientists and post-grads are particularly welcome.
Session Programme - Tuesday 8th July
Chair: Dr Colin Brauner
09:00 Dr Roy Weber (University of Aarhus)
Temperature, a neglected 'allosteric effector' in hemoglobin-oxygen transport [A6.1]
09:20 Dr Frank B Jensen (University of Southern Denmark)
The dual role of red blood cells in tissue oxygen delivery [A6.2]
09:40 Dr Pia Koldkjær (University of Liverpool)
The importance of His a89 for the alkaline Bohr effect in bird haemoglobins [A6.3]
10:00 DrWolfgang Waser (University of Turku)
Bridging the gap: oxygen delivery in the teleost retina [A6.4]
10:20 Refreshment Break
10:50 Dr Michael Berenbrink (University of Liverpool)
Oxygen delivery to the eye and swimbladder of fishes: the ups and downs of the Root effect [A6.5]
11:10 Dr Jodie Rummer (University of British Columbia)
Beyond bouyancy and vision: The potential for the root effect to facilitate oxygen delivery to tissues other than the swim bladder and eye [A6.6]
11:30 Dr Stuart Egginton (University of Birmingham )
Optimising peripheral oxygen transport by means of microvascular remodelling [A6.7]
11:50 Lunch
Chair: Dr David McKenzie
14:00 Prof. Anthony Farrell (University of British Columbia)
Optimizing oxygen delivery to the fish heart [A6.9]
14:20 Dr David McKenzie (CNRS Montpellier)
Does autonomic regulation of heart rate optimise oxygen uptake in teleost fishes? [A6.10]
14:40 Prof. Edwin Taylor (Birmingham University)
Control of cardiorespiratory interactions in fish [A6.11]
15:00 Prof. Tobias Wang (Aarhus University)
Regulation of the cardiac shunt to satisfy oxygen delivery at rest and during increased metabolic rate [A6.12]
15:20 Refreshment Break
15:40 Dr Nini Skovgaard (Indiana University School of Medicine, University of Notre Dame)
Hypoxic pulmonary vasoconstriction in reptiles [A6.13]
16:00 Dr Michael Axelsson (Göteborg University)
Effects of feeding and temperature on gastrointestinal blood flow in the Antarctic fish Pagothenia borchgrevinki; different or just another teleost? [A6.8]
16:20 Prof. Goran Nilsson (University of Oslo)
Hypoxia inducible factor (HIF) - a threat to hypoxic survival? [A6.15]
16:40 Dr Jeffrey Richards (University of British Columbia)
Mechanisms and evolution of hypoxia tolerance in sculpins [A6.16]
