SEBatMarseille2008
Systems Biology
Sponsored by SETAC-UK
Session organised by Dr Claire Grierson (Bristol University), Dr Martin McAinsh (Lancaster University) and Dr Alex Webb (Cambridge University)
This major symposium organised by the plant, cell and animal committees of the SEB brings together the leaders in systems biology to discuss recent developments in systems analysis of developmental and physiological process in animals, plants and microorganisms. The development of high through put technologies that allow parallel analyses of the concentration and dynamics of cellular components has allowed the analysis of biological processes in unprecedented detail. Systems biology is a developing discipline in which computational and mathematical approaches are combined with high throughput experimentation to allow multilevel analysis of biological processes with the aim of gaining new insight. Many systems analyses focus on transcriptomics, proteomics, metabolomics and genomics because the data sets are readily accessible and conform to common archiving protocols. Great insights are already being made, however, using other types of quantitative data. In the age of the computer all data can be digitised but making the data readily accessible to systems approaches requires the establishment of common protocols and archiving strategies. Key to these developments will be incorporating imaging data into systems platforms to allow systems biology to address questions at cellular resolution.
Session Programme
Monday 7th July
10:30 Keynote: Prof. Bela Novak (OCISB, University of Oxford)
Systems biology of the eukaryotic cell cycle [CSS.1]
11:30 Dr Richard Handy (University of Plymouth)
Systems toxicology: can we use the systems biology approach to assess chemical pollutants in the environment? [CSS.2]
12:10 Miss Lucia Vergauwen (University of Antwerp)
A systems biology approach to the effects of chemical and non-chemical stressors in zebrafish [CSS.3]
12:35 Lunch
14:00 Prof. Andrew Cossins (University of Liverpool)
Dissecting the mechanisms of environmental stress adaptation: a systems biology approach [CSS.4]
14:40 Mrs An Hagenaars (University of Antwerp)
Toxicity evaluation of perfluorooctane sulfonate (PFOS) in common carp (Cyprinus carpio): a systems biology approach [CSS.5]
15:05 Refreshment Break
15:45 Miss Adélaïde Lerebours (IRSN)
Comparative analysis of gene expression in brain, liver, skeletal muscle and gills of the zebrafish (Danio rerio) exposed to environmentally relevant uranium water concentrations [CSS.6]
16:10 Prof. Dennis Bray (University of Cambridge)
The chemotaxis receptor cluster revisited [CSS.7]
16:50 Finish: Session continues 9.00 Tuesday 8th July
Tuesday 8th July
09:00 Dr James Schwaber (Thomas Jefferson University)
Systems Biology of Homeodynamics: neuronal adaptive compensation [CSS.8]
09:40 Dr Jing Wang (University of Glasgow)
New view on Drosophila transcriptome [CSS.9]
09:55 Alberto Delgado (National University of Columbia at Bogota)
Digital circuit emulation of gene expression [CSS.10]
10:10 Miss Marleen Eyckmans (University of Antwerp)
Differences in sensitivity to waterborne Cu in three freshwater fish: Effects on oxidative stress and ionregulation [CSS.11]
10:25 Refreshment Break
11:00 Dr Nick Monk (University of Nottingham)
Modelling the mutual support of differential cell fates in the Arabidopsis root epidermis [CSS.12]
11:40 Mr Neil Dalchau (University of Cambridge)
Modelling and simulation of a Ca2+-based feedback loop in the circadian clock of Arabidopsis [CSS.13]
12:05 Lunch
14:00 Workshop: Tools for Systems Biology
17:30 Finish: Session continues 9.00 Wednesday 9th July
Wednesday 9th July
09:00 Prof. Malcolm Bennett (University of Nottingham)
Adopting an integrative systems biology approach to study root growth and development [CSS.14]
09:40 Dr Alistair Middleton (University of Nottingham)
Mathematical modelling of gibberellin signalling [CSS.15]
10:05 Refreshment Break
10:45 Dr Gabriel Krouk (New York University)
A systems approach to nitrogen regulatory networks and the Virtual Plant [CSS.16]
11:25 Dr Alisdair Fernie (Max-Planck-Institut für Molekulare Pflanzenphysiologie) SEB PLANT SECTION PRESIDENT'S MEDALLIST 2008
Integrated genomics approaches using introgression lines of tomato [CSS.17]
12:05 Dr Olga Koroleva (University of Reading, John Innes Centre)
A systematic approach to study location and function of the Exon Junction Complex in plants [CSS.18]
12:30 Lunch
14:00 Prof. Philip Maini (Mathematical Institute, Oxford University)
Modelling aspects of solid cancer growth [CSS.19]
14:40 Prof. Mike White (Liverpool University)
Spatial and temporal information encoding by the NF-κB system [CSS.20]
15:20 Refreshment Break
16:00 Prof. Michael Levine (UC Berkeley MCB)
To Be Confirmed [CSS.21]
