Modelling and in silico biology

Co-convenors: Nick Monk (University of Sheffield) and Leah Band (University of Nottingham)

Over recent decades, we have gained detailed knowledge of many processes involved in plant and animal growth and development. However, with this knowledge comes increasing complexity and a pressing need for mechanistic modelling to uncover how those individual processes interact.
One major challenge is to relate genotypes to phenotypes, requiring researchers to move beyond the network and cellular scales, and use multiscale modelling to predict emergent dynamics at the tissue and organ levels. The Cell and Systems Group aims to promote the use of multiscale modelling. Progress in this area will be crucial as biological research moves from a qualitative to an increasingly quantitative understanding of plant and animal systems, employing predictive tools that accelerate the development of, for example, improved crop varieties.