Super resolution microscopy helping to solve biological questions

31 October 2016 - By: Prof John Girkin

Super resolution microscopy helping to solve biological questions

By Prof John Girkin, Durham University

The profile of super resolution microscopy rose rapidly at the end of 2015 with the award of the Nobel prize for chemistry to several pioneers in the field. The techniques available for super resolution imaging are now very broad and the main focus of this session was to illustrate how these methods can move on to actually help answer real biological questions. The presentations illustrated that this process is now on going with illustrations of the use of these methods to a wide range of biological samples ranging from intact blood vessels through to viruses and plants.
A clear direction for the future of this field is to enable the imaging of more intact samples and crucially to improve the speed of imaging so that more dynamic processes can be viewed. A crucial feature here being both the development of new fluorphores and technological solutions but the integration of this with advanced data-processing is becoming an increasingly important aspect of super resolution applications to biology. Future advances in the field are likely to occur where data from different scales of imaging, chemical specificity and 3D dynamic images are combined.

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Category: Cell Biology