C-terminally encoded peptide (CEP) family

02 March 2014 - By: Christine Raines

C-terminally encoded peptide (CEP) family

By Christine Raines

The JXB publishes high quality manuscripts that address questions of broad interest to plant biologists. A unique feature of JXB is the publication of Special Issues containing reviews or research papers arising from presentations at workshops or meetings. During 2013 we published 5 special issues and have another 10 in the pipeline for 2014 (see page 11). A recently published Special Issue presents papers giving a current view of the emergent field of Peptide Signalling. Although this field is expanding there are only a small number of peptide ligands that have been identified and a biological role demonstrated. In this issue, three papers present data on the C-terminally encoded peptide (CEP) family:

 Ianto Roberts, Stephanie Smith, Bert De Rybel, Jana Van Den Broeke, Wouter Smet, Sarah De Cokere, Marieke Mispelaere, Ive De Smet, and Tom Beeckman The CEP family in land plants: evolutionary analyses, expression studies, and role in Arabidopsis shoot development J. Exp. Bot. (2013) 64 (17): 5371-5381 doi:10.1093/jxb/ert331;

Christina Delay, Nijat Imin, and Michael A. Djordjevic CEP genes regulate root and shoot development in response to environmental cues and are specific to seed plants J. Exp. Bot. (2013) 64 (17): 5383-5394 doi:10.1093/jxb/ert332;

Nijat Imin, Nadiatul A. Mohd-Radzman, Huw A. Ogilvie, and Michael A. Djordjevic The peptide-encoding CEP1 gene modulates lateral root and nodule numbers in Medicago truncatula J. Exp. Bot. (2013) 64 (17): 5395-5409 doi:10.1093/ jxb/ert369. 

Together these papers show that the CEP family is found only in land plants, that they play a role in shoot and root development and that in Medicago truncatulata CEP’s modulate nodule number. Roberts et al and Delay et al used a bioinformatics approach to show that there are 10 additional CEP genes in Arabidopsis and GUS expression analysis and over-expression of this family reveal both tissue specificity and role in root and shoot growth and development. These papers identify new players in cell-to cell communication and the next challenge is to undertake biochemical studies to identify the components in the signalling pathway for the CEP’s.


Category: Plant Biology
Christine raines

Christine Raines

Christine Raines is a Professor of Plant and Molecular Physiology at the University of Essex as well as being Editor in Chief of the Journal of Experimental Botany. Christine is also a member of the SEB Plant Sections Committee and the SEB Council.